The platform evaluates potential undesirable effects on the physiological functions of drugs, particularly focusing on the central nervous system (CNS), cardiovascular system, and respiratory system.

Core Combination Tests:
-Cardiovascular System: Awake dog/pig/monkey with implantable telemetry systems and vest telemetry (JET) systems .
-Respiratory System: EMKA whole-body plethysmography system for mouse/rat studies.
-CNS: Functional observation battery (FOB), Modified Irwin method, In vitro electrophysiology (Potassium ion channel (hERG) testing)

Additional Experiments:
-Cardiovascular System: Myocardial contractive power, action potential, sodium and calcium ion channels, markers of cardiotoxicity.
-Respiratory System: Airway resistance studies.
-CNS: Behavioral, learning, and memory evaluations, electrophysiological examination.

Supplementary Experiments:
-Gastrointestinal System
-Urinary/Renal System
-Neuromuscular Function and Coordination