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Research platforms
Non-clinical Safety Evaluation and Research Platform
Genetic toxicology

The platform provides a comprehensive suite of genetic toxicology assays, including the Ames test, chromosomal aberration assays, gene mutation tests, micronucleus tests, and comet assays, both in vitro and in vivo.


Core Combination Tests:
-Ames trial
-Chromosomal aberration assays (in vitro and in vivo)
-Gene mutation tests (MLA, HGPRT, XGPRT)
-Micronucleus test (in vitro and in vivo)
 -Comet assay of multiple organs in vivo


Additional Trials/Mechanism Studies:
-Pig-a gene mutation assay (in vitro and in vivo)
-Multi-biomarker genotoxicity tests (in vitro)
-In vivo liver micronucleus tests

 

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