Various safety tests are conducted to assess local irritation, allergic reactions, hemolysis, and inhalation toxicity. These tests ensure that drugs are safe for administration in various forms.
Local Irritation Tests
-Vascular irritation test
-Muscle irritation test
-Skin irritation test
-Mucosal irritation test
-Eye irritation test
-Nasal drip and inhalation irritation test
-Vaginal irritation test
-Rectal irritation test
-Oral drug irritation test
Allergenicity Tests (mouse, rat, guinea pig)
-Active systemic allergy test
-Passive skin allergy test
-Active skin allergy test
-Guinea pig Buehler test (BT)
-Guinea pig maximization test (GPMT)
-Skin Photoallergic reaction test
Hemolysis Tests
-In vitro hemolysis assay
-In vivo hemolysis assay
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